Human papillomavirus

Advisory report on the Human Papillomavirus (HPV) Vaccination Schedule

A lot of new data on the immunogenicity, efficacy and effectiveness of fewer than three doses of HPV vaccine have become available since the publication of the CIQ report on the 2012 knowledge update. The two-dose schedule has become a standard that is widely accepted around the world. Such schedules are currently in use in more than half (48/82) of the countries offering HPV vaccination programs. The same schedule has been approved and recommended by the World Health Organization (W HO) and…

Scientific advisory

HPV Immunization of Quebec Pre-Adolescents: Two or Three Doses?

In 2007, the Comité sur l’immunisation du Québec (CIQ) recommended an extended schedule exclusively for immunization against the human papilloma virus (HPV) starting in grade 4 (0, 6, 60 months); the committee also stated that the third dose should be administered “if judged necessary.” Since the introduction of the Québec HPV immunization program in 2008, similar programs (two doses administered six months apart and a possible third dose if necessary) have been introduced in Mexico and…

Scientific advisory

HPV Vaccination in Québec: Knowledge Update and Expert Panel Proposals

The human papillomavirus (HPV) belongs to the Papillomaviridae family, which includes at least 100 genotypes affecting the skin and mucous membranes. Of these, about 40 affect the anogenital area in particular, and approximately 15 are oncogenic. Genotypes 16 and 18 are responsible for 70-76% of cervical cancer cases worldwide. Genotypes 6 and 11 are non-oncogenic but are responsible for most cases of condyloma (anogenital warts [AGW]).

HPV prevalence and incidence…

Scientific advisory

Advice of the Institut national de santé publique du Québec on human papillomavirus vaccines

In October 2007, the Comité sur l'immunisation du Québec (CIQ) tabled a report entitled “Prévention par la vaccination des maladies attribuables aux virus du papillome humain au Québec” [Prevention of diseases caused by human papillomaviruses through vaccination]. At the time that report was being drafted, only one vaccine – Gardasil – was authorized for sale in Canada. The report did not directly compare the Gardasil and Cervarix vaccines.

Given the likelihood that the Cervarix…

Scientific advisory

Prevention by vaccination of diseases attributable to the Human Papilloma Virus in Québec

The problem of the prevention of diseases attributable to the human papilloma virus (virus du papillome humain) (HPV) extends beyond the field of infectious diseases traditionally prevented by vaccination. This is why the CIQ has followed a different procedure for the preparation of this report by working with a large group of experts, notably from gynaecologists involved with the fight against cancer and from sexually transmitted infectious diseases areas.

The synthesis of facts was…

Research report, study and analysis

Human Papillomavirus (HPV) Infection

Human papillomavirus (HPV) infection is recognized as one of the most common – if not the most common – sexually transmitted infections. The association between HPV and cervical cancer has also been recognized, while more recently it has been associated with some other types of cancer, primarily those in the genital region.

Our understanding of HPV has advanced considerably in the past decade. In fact, we now speak of human papillomavirus infections since there are roughly 100…

Knowledge review